There are too many tweaks to cover in any single post but some you might want to look at include:
- Visual Effects – set to best performance.
- Force unloading unused DLLs from memory
- If you use a third-party ZIP archive tool (7-Zip anyone?) turn off browsing archives
- Increase the L2 cache and file system caching memory size
- Disable recent shares in Network Places
- Remove unnecessary performance robbing Autostart programs such as Adobe Reader